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Polyprenols from the needles of Taxus chinensis var. mairei

Author:
Yu, Jinhui, Wang, Yanbin, Qian, Hua, Zhao, Yunpeng, Liu, Bentong, Fu, Chengxin
Source:
Fitoterapia 2012 v.83 no.5 pp. 831-837
ISSN:
0367-326X
Subject:
Taxus wallichiana var. mairei, mass spectrometry, nuclear magnetic resonance spectroscopy, polyprenols, reversed-phase high performance liquid chromatography, China
Abstract:
Polyprenols with various pharmacological activities were first isolated from Taxus chinensis var. mairei, which is native to China, and were identified by a high performance liquid chromatography/mass spectrometry (HPLC/MS), ¹H nuclear magnetic resonance (¹H NMR), ¹³C NMR and infrared (IR) spectroscopy. The taxus polyprenols (TPs) had two maxima of polyprenol-17 and polyprenol-21 and different from polyprenols distributed in other plant species. A reversed-phase HPLC method with a simple gradient elution was established, and the proposed combined peak area method for the quantification of polyprenols was verified. The analysis indicated that TPs were present in the old needles at levels as high as 3% and that T. chinensis var. mairei could be an alternative botanical source for the extraction of polyprenols.
Agid:
395226