Jump to Main Content
Absence of Serotype-Specific Surface Antigen in Laboratory Variants of Epidemic-Associated Listeria monocytogenes Strains
- Cheng, Ying, Yue, Lili, Elhanafi, Driss, Kathariou, S.
- Applied and environmental microbiology 2007 v.73 no.19 pp. 6313-6316
- Listeria monocytogenes, bacteriophages, clones, monoclonal antibodies, serotypes, surface antigens
- Variants that lacked reactivity with the serotype 4b-specific monoclonal antibody c74.22 and that lost susceptibility to certain Listeria- or serotype 4b-specific phages were identified in the course of genetic studies with serotype 4b Listeria monocytogenes strains H7550 and F2381L (epidemic clones I and II, respectively). Our findings suggest that such variants can become inadvertently established under laboratory conditions and suggest caution in work involving serotype 4b strains and genetic constructs thereof.