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Synthesis and antibacterial activity of betulin esters

Author:
Chue, K.-T., Chang, M.-S., Ten, L. N.
Source:
Chemistry of natural compounds 2011 v.47 no.4 pp. 583-586
ISSN:
0009-3130
Subject:
Ochrobactrum anthropi, Stenotrophomonas maltophilia, antibacterial properties, benzoates, betulin, chlorides
Abstract:
Betulin isonicotinate, 6-chloronicotinate, 2-chlorocinnamate, and benzoates were synthesized by the reaction of betulin and the acid chlorides. It was shown that the 3,4-difluorobenzoate exhibited antibacterial activity against Ochrobactrum anthropi, Stenotrophomonas maltophilia, and S. nitritireducens whereas the 3,5-dinitrobenzoate was active against the last two microorganisms.
Agid:
410280