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Acute toxicity of peracetic acid (PAA) formulations to Ichthyophthirius multifiliis theronts

Author:
Straus, David L., Meinelt, Thomas
Source:
Parasitology research 2009 v.104 no.5 pp. 1237
ISSN:
0932-0113
Subject:
Ichthyophthirius multifiliis, antimicrobial properties, peracetic acid, disinfectants, toxicity, developmental stages
Abstract:
Peracetic acid (PAA) is an antimicrobial disinfectant used in agriculture, food processing, and medical facilities. It has recently been suggested as a means to control infestations of Ichthyophthirius multifiliis. The purpose of this study was to determine the acute toxicity of two products containing 4.5% and 40% PAA to I. multifiliis theronts from two geographically separate isolates. Theronts were exposed to concentrations of PAA in 96-well plates containing groundwater at 23°C. Acute toxicity was observed over a 4-h period. No significant difference in the median lethal concentration (LC₅₀) estimates was evident between the two isolates at 4 h with the 4.5% PAA product (0.146 versus 0.108 mg/l PAA), while there was a statistical difference between the 4 h LC₅₀ with the 40% PAA product (0.274 versus 0.158 mg/l PAA). These results suggest that PAA is toxic to I. multifiliis theronts at low concentrations and that one of the isolates was more resistant to this compound.
Agid:
42273
Handle:
10113/42273