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Hypogammaglobulinaemia and lipaemia initiated by the murine sarcoma virus (Moloney) in rats

Author:
Perk, K., Shachat, D. A., Moloney, J. B.
Source:
Laboratory animals 1972 v.6 no.3 pp. 315-320
ISSN:
1758-1117
Subject:
albumins, blood serum, cholesterol, chylomicrons, electrophoresis, enzymes, fatty acid composition, gamma-globulins, hyperlipidemia, laboratory animals, mice, rats, sarcoma, viruses
Abstract:
Chemical and electrophoretic studies of serum obtained from rats bearing tumours induced by murine sarcoma virus (Moloney) revealed a substantial drop in γ-globulin level and, to a lesser degree, in the albumin level. The α-1 and α-2 globulin fraction levels rose sharply. Also elevated were serum total fatty acids, serum cholesterol levels, lipoprotein (almost entirely associated with the β-lipoprotein and chylomicrons fractions) and the serum glutamic oxalacetic transaminase level.
Agid:
4296028