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Bioinformatic comparison of human and higher plant phosphatomes
- Samofalova, D. A., Karpov, P. A., Blume, Ya. B.
- Cytology and genetics 2015 v.49 no.4 pp. 207-219
- Arabidopsis thaliana, Oryza sativa, Physcomitrella patens, Zea mays, active sites, animal proteins, bioinformatics, humans
- The study presents the results of bioinformatic comparison of protein phosphatases from higher plants and human phosphatome (150 proteins). Based on sequence and profile comparison with known catalytic domains, 204 plant homologues were selected from Physcomitrella patens and Arabidopsis thaliana. Clustering of joint group of plant and animal protein phosphatases revealed fundamental differences in plant and human phosphatomes. At the same time, significant differences in the sets of protein phosphatases in P. patens, A. thaliana, Orysa sativa, and Zea mays were shown.