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Magnetic nanoparticles: material engineering and emerging applications in lithography and biomedicine
- Bao, Yuping, Wen, Tianlong, Samia, Anna Cristina S., Khandhar, Amit, Krishnan, Kannan M.
- Journal of materials science 2016 v.51 no.1 pp. 513-553
- drugs, engineering, humans, image analysis, iron oxides, magnetic resonance imaging, medicine, nanoparticles, pharmacokinetics
- We present an interdisciplinary overview of material engineering and emerging applications of iron oxide nanoparticles. We discuss material engineering of nanoparticles in the broadest sense, emphasizing size and shape control, large-area self-assembly, composite/hybrid structures, and surface engineering. This is followed by a discussion of several nontraditional, emerging applications of iron oxide nanoparticles, including nanoparticle lithography, magnetic particle imaging, magnetic guided drug delivery, and positive contrast agents for magnetic resonance imaging. We conclude with a succinct discussion of the pharmacokinetics pathways of iron oxide nanoparticles in the human body—an important and required practical consideration for any in vivo biomedical application, followed by a brief outlook of the field.