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Chemical composition, antioxidant and antimicrobial activity of the essential oil from the leaves of Macleaya cordata (Willd) R. Br.

Author:
Li, Chun-Mei, Yang, Xiao-Yong, Zhong, Yi-Rong, Yu, Jian-Ping
Source:
Natural product research 2016 v.30 no.4 pp. 438-442
ISSN:
1478-6427
Subject:
Macleaya cordata, Staphylococcus aureus, anti-infective agents, anti-infective properties, antioxidant activity, antioxidants, bacteria, cell membranes, chemical composition, essential oils, gas chromatography, hydrodistillation, leaves, mass spectrometry, minimum inhibitory concentration, scanning electron microscopy
Abstract:
The essential oil from the leaves of Macleaya cordata R.Br. obtained by hydrodistillation was analysed by gas chromatography/mass spectrometry. Sixty-eight compounds consisting of up to 92.53% of the essential oil were identified. Antioxidant activities of the essential oil were evaluated by using DPPH radical scavenging and β-carotene–linoleic acid assays. The essential oil showed moderate antioxidant activity. In addition, the essential oil exhibited potential antimicrobial activity against all tested microorganisms, with diameters of inhibition zones ranging from 8.7 ± 0.5 to 17.2 ± 1.2 mm and minimum inhibitory concentration values from 125 to 500 μg/mL. We selected the most sensitive bacterium Staphylococcus aureus as model to observe of the action of essential oils of M. cordata on the membrane structure by scanning electron microscopy. The treated cell membranes were damaged severely. The results presented here indicate that the essential oil of M. cordata may be potential sources of antioxidant and antimicrobial agents in the future.
Agid:
4790429