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Age-dependent competition of porcine enterotoxigenic <i>E. coli</i> (ETEC) with different fimbria genes — Short communication

Author:
Hur, Jin, Lee, Kyeong Min, Lee, John Hwa
Source:
Acta veterinaria Hungarica 2011 v.59 no.4 pp. 411-417
ISSN:
0236-6290
Subject:
adhesins, diarrhea, enterotoxigenic Escherichia coli, fimbriae, genes, hemolysis, piglets, suckling
Abstract:
To investigate the association of pathogenic <i>Escherichia coli</i> fimbrial adhesins with the development of diarrhoea in piglets of different age groups and to test their relative competitiveness, piglets were orally inoculated with a mixture of <i>E. coli</i> strains harbouring F4, F5, F6, F18 and F41 fimbrial genes. A total of 537 <i>E. coli</i> strains with haemolytic activity were isolated from 36 diarrhoeic piglets. The F4 fimbrial gene was observed in 98.5%, 97.6% and 80.6% strains carrying fimbrial genes isolated from diarrhoeic piglets that were infected at 1, 3 and 5 weeks of age, respectively. These data demonstrate that F4 fimbriae are highly associated with diarrhoea in piglets of all age groups. Interestingly, the F18 fimbrial gene was observed in 2.4% and 25.4% strains carrying fimbrial genes isolated from the 3- and 5-week-old groups, respectively, which confirms that F18 fimbriae are associated with diarrhoea in piglets from late stages of suckling to post-weaning, and are more related to diarrhoea in weaned than in unweaned piglets.
Agid:
4799848