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A new phenyldilactone from Lespedeza cuneata
- Jiang, Wei, Ye, Ji, Xie, Yang-Guo, Pan, Ya-Ping, Zheng, Yue, Qian, Xiu-Ping, Jin, Hui-Zi
- Journal of Asian natural products research 2016 v.18 no.2 pp. 200-205
- Lespedeza cuneata, aerial parts, cytotoxicity, humans, in vitro studies, neoplasm cells, nuclear magnetic resonance spectroscopy
- A new phenyldilactone, maysedilactone B (1), together with twenty known compounds, were isolated from the aerial parts of Lespedeza cuneata . The structural elucidation of the isolated compounds was primarily based on HR-ESI-MS, IR and 1D and 2D NMR analyses. Compounds 1 – 8 and 15 – 21 were tested for cytotoxicity against four human tumor cell lines (A549, HCT116, SKOV3, and HepG2) using MTT method in vitro , while no significant activities were observed for the evaluated compounds.