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Structural characteristics and antitumor activity of a new chrysolaminaran from the diatom alga Synedra acus

Author:
Kusaikin, M. I., Ermakova, S. P., Shevchenko, N. M., Isakov, V. V., Gorshkov, A. G., Vereshchagin, A. L., Grachev, M. A., Zvyagintseva, T. N.
Source:
Chemistry of natural compounds 2010 v.46 no.1 pp. 1-4
ISSN:
0009-3130
Subject:
Synedra, colon, molecular weight, neoplasms
Abstract:
The 1→3;1→6-β-D-glucan chrysolaminaran with molecular weight 8.5 kDa and 3.6:1 ratio of 1→3:1→6 bonds was isolated from cultivated diatom alga Synedra acus and characterized. It was shown that the isolated chrysolaminaran inhibited growth and colony formation of human colon tumor cells.
Agid:
496227