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The role of siderophores in metal homeostasis of members of the genus Burkholderia

Author:
Mathew, Anugraha, Jenul, Christian, Carlier, Aurelien L., Eberl, Leo
Source:
Environmental microbiology reports 2016 v.8 no.1 pp. 103-109
ISSN:
1758-2229
Subject:
Burkholderia, homeostasis, siderophores, toxicity, zinc
Abstract:
Although members of the genus Burkholderia can utilize a high‐affinity iron uptake system to sustain growth under iron‐limiting conditions, many strains also produce siderophores, suggesting that they may serve alternative functions. Here we demonstrate that the two Burkholderia siderophores pyochelin and ornibactin can protect the cells from metal toxicity and thus play an alternative role in metal homeostasis. We also demonstrate that metals such as copper and zinc induce the production of ornibactin.
Agid:
5143438