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Chemical composition, N-nitrosamine inhibition and antioxidant and antimicrobial properties of essential oil from Coreopsis tinctoria flowering tops

Author:
Yao, Xincheng, Wang, Xinbing, Gu, Chengzhi, Zeng, Hong, Chen, Wen, Tang, Hui
Source:
Natural product research 2016 v.30 no.10 pp. 1170-1173
ISSN:
1478-6427
Subject:
Coreopsis tinctoria, anti-infective properties, antioxidant activity, antioxidants, chemical composition, essential oils, flowering, gas chromatography-mass spectrometry, hydrodistillation, inhibitory concentration 50, mountains, nitrosamines, oils, tea, China
Abstract:
Coreopsis tinctoria flowering (CTF) tops from the Kunlun Mountains in Xinjing (north-western China) have been used for tea production for about a century. This study was to assess antioxidant, nitrite-scavenging and N -nitrosamine inhibitory and antimicrobial activities of the essential oil extracted from CTF tops. The essential oil was extracted through hydrodistillation and its chemical compositions were analysed by GC–MS. Seventy compounds of the oil were identified, representing 81.87% of total oil. The antioxidant capacities of the oil with IC ₅₀ values for scavenging DPPH and ABTS were 287.66 ± 12.60 and 1.251 ± 0.127 μg mL ⁻ ¹, respectively. The nitrite-scavenging and N -nitrosamine inhibitory activities (IC ₅₀) were 0.3912 ± 0.0127 and 0.6564 ± 0.036 μg mL ⁻ ¹, respectively. The oil has a certain antimicrobial capacity, but its capacity was weaker than that of penicillinG (24 μg mL ⁻ ¹). The oil showed antioxidant and antimicrobial capacities and had a stronger nitrite-scavenging and N -nitrosamine inhibitory properties.
Agid:
5190230