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Limonoids from the Endemic Brazilian Species Raulinoa echinata

Author:
Biavatti, Maique W., Vieira, Paulo C., Silva, M. Fatima G. F. da, Fernandes, João B., Albuquerque, Sérgio
Source:
Zeitschrift für Naturforschung 2014 v.56 no.7-8 pp. 570-574
ISSN:
1865-7125
Subject:
Rutaceae, Trypanosoma cruzi, bioactive properties, leaves, limonin, limonoids, stems, surveys
Abstract:
Phytochemical survey of stems and leaves of the South Brazilian endemic Raulinoa echinata Cowan, Rutaceae led to the isolation of five limonoid derivatives: the widespread limonin, limonexic acid, kihadalactone B, a methoxylated limonexic acid derivative and a degraded limonoid structurally related to fraxinellone. The two latter compounds have been isolated for the first time. These compounds displayed weak inhibitory activity when assayed in vitro against trypomastigote forms of Trypanosoma cruzi. In this paper, the isolation, structure elucidation and bioactivity of these compounds are reported
Agid:
5230060