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Racing Induces Changes in the Blood Concentration of Serum Amyloid A in Thoroughbred Racehorses
- Turło, Agnieszka, Cywińska, Anna, Czopowicz, Michał, Witkowski, Lucjan, Jaśkiewicz, Anna, Winnicka, Anna
- Journal of equine veterinary science 2016 v.36 pp. 15-18
- Thoroughbred, acute phase proteins, amyloid, analysis of variance, blood serum, enzyme-linked immunosorbent assay, exercise, racehorses, sports
- Intensive exercise results in the increased blood concentration of the acute phase proteins in horses competing in some sport disciplines. In this study, the blood level of serum amyloid A (SAA) was analyzed in Thoroughbred racehorses during 5 days after completion of the race. Samples were collected from 25 healthy Thoroughbred horses beginning with 4 hours after the race and repeated daily up to the fifth day after the race. Serum amyloid A analysis was performed using commercial enzyme-linked immunosorbent assay kit, and the results were presented as median, interquartile range (IQR), and range. Data were analyzed using Friedman's nonparametric analysis of variance. The acute phase response (APR) was reflected by an increased SAA level after the race, reaching significantly higher concentrations on days 1 (P < .001) and 2 (P = .005) and falling below the level of the first sample on day 5 (P = .006). The median peak concentration observed on day 1 after the race was 3.84 mg/L (IQR, 2.32 to 8.86). Racing induces minute changes in SAA concentration typical for the exercise-induced APR; however, the significance of this reaction in the context of horse health and fitness remains unclear.