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Effects of glutathione on acid stress resistance and symbiosis between Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus

Author:
Wang, Ting, Xu, Zhenshang, Lu, Shiyi, Xin, Min, Kong, Jian
Source:
International dairy journal 2016 v.61 pp. 22-28
ISSN:
0958-6946
Subject:
Lactobacillus delbrueckii subsp. bulgaricus, Streptococcus thermophilus, acid tolerance, cytoplasm, fermentation, genes, glutathione, glutathione synthase, mutants, protective effect, symbiosis, yogurt
Abstract:
Streptococcus thermophilus SDMCC18 contains a novel bi-functional glutathione synthetase gene gshF, and it can produce glutathione (GSH). In the present study, we demonstrated that the produced GSH by S. thermophilus SDMCC18 could protect cells against acid challenge and be secreted into the medium. Moreover, using a gshF-defective mutant strain as the control, we found that the GSH conferred a protective role against acid stress to Lactobacillus delbrueckii subsp. bulgaricus ATCC11842. In addition, L. bulgaricus ATCC11842 could import the exogenous GSH into the cytoplasm, leading to an improved growth of strain ATCC11842. Taken together, our study reported a novel proto-cooperation relationship between S. thermophilus and L. bulgaricus in yoghurt fermentation.
Agid:
5266547