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Phytochemical investigation of Pseudelephantopus spiralis (Less.) Cronquist

Author:
Jimenez Usuga, Nora del Socorro, Malafronte, Nicola, Durango, Edison Javier Osorio, Braca, Alessandra, De Tommasi, Nunziatina
Source:
Phytochemistry letters 2016 v.15 pp. 256-259
ISSN:
1874-3900
Subject:
Pseudelephantopus, aerial parts, neoplasms, nuclear magnetic resonance spectroscopy, sesquiterpenoids
Abstract:
Three new sesquiterpenes, 1β,4β,1α,10α-diepoxy-6-oxo-7α,8α-diacetoxygermacr-11-en-12-oic acid methyl ester named as spiraloside (1), 1α,10α-epoxy-8α,13-diacetylpiptocarphol (2), and 5β-(2-methylacryloyloxy)spicatocadinanolide A (3) along with two known compounds were isolated from Pseudelephantopus spiralis aerial part extracts. Their structures were determined by spectroscopic and spectrometric techniques including 1D-, 2D NMR, and MS analyses. Compounds 1–3 were assayed against PC-3 and MCF-7 cancer cell lines, showing no activity.
Agid:
5278680