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Phytochemical investigation of Pseudelephantopus spiralis (Less.) Cronquist
- Nora del Socorro Jimenez Usuga, Nicola Malafronte, Edison Javier Osorio Durango, Alessandra Braca, Nunziatina De Tommasi
- Phytochemistry letters 2016 v.15 pp. 256-259
- Pseudelephantopus, aerial parts, neoplasms, nuclear magnetic resonance spectroscopy, sesquiterpenoids
- Three new sesquiterpenes, 1β,4β,1α,10α-diepoxy-6-oxo-7α,8α-diacetoxygermacr-11-en-12-oic acid methyl ester named as spiraloside (1), 1α,10α-epoxy-8α,13-diacetylpiptocarphol (2), and 5β-(2-methylacryloyloxy)spicatocadinanolide A (3) along with two known compounds were isolated from Pseudelephantopus spiralis aerial part extracts. Their structures were determined by spectroscopic and spectrometric techniques including 1D-, 2D NMR, and MS analyses. Compounds 1–3 were assayed against PC-3 and MCF-7 cancer cell lines, showing no activity.