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Cardiomyopathy prevalence in 780 apparently healthy cats in rehoming centres (the CatScan study)

Jessie Rose Payne, David Charles Brodbelt, Virginia Luis Fuentes
Journal of veterinary cardiology 2015 v.17 pp. S244
adults, body condition, body weight, cardiomyopathy, cats, confidence interval, cross-sectional studies, echocardiography, heart, males, regression analysis, systolic blood pressure
Hypertrophic cardiomyopathy (HCM) appears to be common in cats and, based on pilot data, a prevalence of 15% has been hypothesized. The objectives were to screen a large population of apparently healthy adult cats for cardiac disease, and identify factors associated with a diagnosis of HCM.A total of 1007 apparently healthy cats ≥6 months of age.In this prospective, cross-sectional study, the inclusion criteria were: apparently healthy cats, aged ≥6 months, available for rehoming over a 17-month period from two rehoming centres. Hypertensive or hyperthyroid cats were excluded. Body weight, body condition score, auscultation, systolic blood pressure and two-dimensional (2-D) echocardiography were evaluated. Cats with left ventricular end-diastolic wall thickness ≥6 mm on 2-D echocardiography were considered to have HCM.Complete data were obtained in 780 cats. Heart murmur prevalence was 40.8% (95% confidence interval (CI) 37.3–44.3%), 70.4% of which were considered functional. The prevalence of HCM was 14.7% (95% CI 12.3–17.4%), congenital disease 0.5% (95% CI 0.1–1.3%), and other cardiomyopathies 0.1% (95% CI 0.0–0.7%). The HCM prevalence increased with age. The positive predictive value of a heart murmur for indicating HCM was 17.9–42.6% (higher in old cats), and the negative predictive value was 90.2–100% (higher in young cats). The factors associated with a diagnosis of HCM in binary logistic regression models were male sex, increased age, increased body condition score and a heart murmur (particularly grade III/VI or louder).Hypertrophic cardiomyopathy is common in apparently healthy cats, in contrast with other cardiomyopathies. Heart murmurs are also common, and are often functional.