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Virulence, persistence and dissemination of Mycoplasma bovis
- Bürki, Sibylle, Frey, Joachim, Pilo, Paola
- Veterinary microbiology 2015 v.179 no.1-2 pp. 15-22
- Mycoplasma bovis, adhesion, arthritis, biofilm, cattle, cattle diseases, hydrogen peroxide, immune system, keratoconjunctivitis, lipoproteins, mastitis, mycoplasmosis, otitis, pathogen survival, pathogens, pneumonia, secondary metabolites, virulence
- Bovine mycoplasmosis due to Mycoplasma bovis causes several important bovine diseases such as pneumonia, mastitis, arthritis, otitis, genital disorders or keratoconjunctivitis. Variable surface lipoproteins, adhesion, invasion of host cells, modulation of the host immune system, biofilm formation and the release of secondary metabolites like hydrogen peroxide, as well as synergistic infections with other bacterial or viral pathogens are among the more significantly studied characteristics of the bacterium.The aim of this review is to summarize the current knowledge regarding the virulence of M. bovis and additionally, factors contributing to the dissemination and persistence of this pathogen in the bovine host will be discussed.