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Application of Mechanochemical Pretreatment Prior to Aqueous Extraction of Eleutheroside B from Eleutherococcus senticosus

Author:
Jin, Liji, Li, Huaqiang, Wu, Feifei, Li, Xiaoyu, Yu, Haibo, Cui, Naizhong, You, Jiansong, Cao, Zhenhui, Sun, Xiuhua, Zhang, Jiancheng, Wang, Xiaoli, Song, Chunna, Li, Shuying, Xu, Yongping
Source:
Industrial & Engineering Chemistry Research 2012 v.51 no.32 pp. 10695-10701
ISSN:
1520-5045
Subject:
Eleutherococcus senticosus, chemistry, engineering, experimental design, particle size, solvents, sustainable technology, water temperature
Abstract:
A mechanochemical pretreatment was used prior to aqueous extraction of eleutheroside B from Eleutherococcus senticosus. The effects of the mechanochemical assisted extraction parameters hydroxypropyl-β-cyclodextrin (HP-β-CD) content, particle size, and circulating water temperature on the extraction yield of eleutheroside B were investigated. The mechanochemical assisted extraction process was optimized based on an orthogonal experimental design. The optimum process conditions were a HP-β-CD content of 23% (w/w), a particle size of D₉₅ ≤ 44 μm and circulating water temperature of 40 °C. The mechanochemical assisted extraction process produced a higher eleutheroside B extraction yield, using a shorter extraction time and a greatly simplified process compared with traditional heat-reflux extraction, which makes mechanochemical assisted extraction a potential tool for eleutheroside B extraction from Eleutherococcus senticosus. Moreover, this technique used water as the solvent, making mechanochemical assisted extraction a less expensive and eco-friendly technique compared with traditional heat-reflux extraction.
Agid:
5369097