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Visible-Light-Induced Bactericidal Activity of a Nitrogen-Doped Titanium Photocatalyst against Human Pathogens

Author:
Wong, Ming-Show, Chu, Wen-Chen, Sun, Der-Shan, Huang, Hsuan-Shun, Chen, Jiann-Hwa, Tsai, Pei-Jane, Lin, Nien-Tsung, Yu, Mei-Shiuan, Hsu, Shang-Feng, Wang, Shih-Lien, Chang, Hsin-Hou
Source:
Applied and environmental microbiology 2006 v.72 no.9 pp. 6111-6116
ISSN:
0099-2240
Subject:
Acinetobacter baumannii, Escherichia coli, Listeria monocytogenes, Shigella flexneri, Staphylococcus aureus, Streptococcus pyogenes, Vibrio parahaemolyticus, antibacterial properties, humans, pathogens, titanium, titanium dioxide, ultraviolet radiation
Abstract:
The antibacterial activity of photocatalytic titanium dioxide (TiO₂) substrates is induced primarily by UV light irradiation. Recently, nitrogen- and carbon-doped TiO₂ substrates were shown to exhibit photocatalytic activities under visible-light illumination. Their antibacterial activity, however, remains to be quantified. In this study, we demonstrated that nitrogen-doped TiO₂ substrates have superior visible-light-induced bactericidal activity against Escherichia coli compared to pure TiO₂ and carbon-doped TiO₂ substrates. We also found that protein- and light-absorbing contaminants partially reduce the bactericidal activity of nitrogen-doped TiO₂ substrates due to their light-shielding effects. In the pathogen-killing experiment, a significantly higher proportion of all tested pathogens, including Shigella flexneri, Listeria monocytogenes, Vibrio parahaemolyticus, Staphylococcus aureus, Streptococcus pyogenes, and Acinetobacter baumannii, were killed by visible-light-illuminated nitrogen-doped TiO₂ substrates than by pure TiO₂ substrates. These findings suggest that nitrogen-doped TiO₂ has potential application in the development of alternative disinfectants for environmental and medical usages.
Agid:
537616