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Ameliorative response of some essential oil furanocoumarins and proteins from Psoralea corylifolia against gamma-irradiation induced oxidative stress

Bhat, Towseef Mohsin, Choudhary, Sana, Ansari, M.Y.K., Aslam, Rumana, Ahmed Dar, Sabzar
Industrial crops and products 2015 v.76 pp. 422-431
Cullen corylifolium, antioxidant activity, antioxidants, biomarkers, biosynthesis, catalase, chromosome aberrations, dose response, environmental factors, essential oils, gamma radiation, hydrogen peroxide, oxidative stress, peroxidase, proteins, psoralens, radio, superoxide dismutase
Secondary metabolism producing essential oil furanocoumarins depends on various environmental factors and ionizing radiation is currently a very important way of enhancing these compounds through radio stimulation. The study aims to evaluate the ameliorative effect of essential oil furanocoumarins and proteins from Psoralea corylifolia against gamma-irradiation-induced oxidative stress. Antioxidant biomarkers like H2O2, peroxidase, superoxide dismutase, and catalase increased significantly (p<0.01) in all treated groups. Dose dependent increase of H2O2 concentration leads to significant chromosomal abnormalities. Essential oil (EO) yield and furanocoumarin content showed a significant (p<0.01) increase up to 200Gy. These contents decreased significantly on increased expression of proteins involved in furanocoumarin biosynthesis and stress defense. DPHH and Phosphomolybdenum assays showed a significant (p<0.01) antioxidant activity in the essential oil on varying doses of gamma radiation. It is concluded that mild doses of gamma irradiation is an important abiotic-elicitor for enhancing the essential oil yield and furanocoumarin content in P. corylifolia which possess important radio resistant properties.