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Regioisomeric acylated polyhydroxy triterpenoids from the stems of Barringtonia racemosa

Author:
Annam, Suresh Chandra Venkata Appa Rao, Madhu, Ankireddy, Mangala Gowri, Ponnapalli, Raju, Tuniki Venugopal, Pardhasaradhi, Bobbili Veera Venkata
Source:
Phytochemistry letters 2015 v.13 pp. 370-374
ISSN:
1874-3900
Subject:
Barringtonia racemosa, betulinic acid, cytotoxicity, human cell lines, lupeol, neoplasm cells, spectral analysis, stems
Abstract:
From the stem of Barringtonia racemosa two new regioisomeric oleanane-type triterpenes were isolated and characterized as racemosol B (1) and isoracemosol B (2). The structures were elucidated by the use of spectroscopic methods. In addition, the known compounds lupeol, betulinic acid and bartogenic acid were identified. Racemosol B was evaluated for cytotoxicity against a panel of human tumor cell lines, A-549, MDA-MB-231, HeLa, and K-562 and showed moderate but cell-type selective activity.
Agid:
5443154