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Titanium dioxide nanoparticles relieve biochemical dysfunctions of fifth-instar larvae of silkworms following exposure to phoxim insecticide

Author:
Li, Bing, Hu, Rengping, Cheng, Zhe, Cheng, Jie, Xie, Yi, Gui, Suxin, Sun, Qingqing, Sang, Xuezi, Gong, Xiaolan, Cui, Yaling, Shen, Weide, Hong, Fashui
Source:
Chemosphere 2012 v.89 no.5 pp. 609-614
ISSN:
0045-6535
Subject:
aspartate transaminase, foods, silk, silkworms, hemolymph, malate dehydrogenase, insect larvae, drugs, alanine transaminase, glucose, lactate dehydrogenase, poisoning, metabolism, insect pests, phoxim, titanium dioxide, nontarget organisms, proteins, uric acid, free amino acids, succinate dehydrogenase (quinone), urea, nanoparticles
Abstract:
Phoxim insecticide is widely used in agriculture, which is toxic to insect pests and nontarget organisms. The phoxim poisoning is hard to prevent for silkworms. TiO₂ NPs have been widely applied in whitening, brightening foods, toothpaste or sunscreens, and orally-administered drugs. However, whether TiO₂ NPs can increase resistance of silkworm to phoxim poisoning has not been reported. The results demonstrated that added TiO₂ NPs significantly decreased reduction of protein, glucose and pyruvate contents, lactate dehydrogenase, succinate dehydrogenase and malate dehydrogenase activities, and attenuated increases of free amino acids, urea, uric acid and lactate levels, activities of protease, alanine aminotransferase and aspartate aminotransferase in the hemolymph of silkworms caused by phoxim exposure. From the present study, it is clearly evident that added TiO₂ NPs may relieve toxic impacts of phoxim insecticide on silkworm metabolism, which in turn may result in an increase in silk yield.
Agid:
545053