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Chemical characteristics of different parts of Coreopsis tinctoria in China using microwave‐assisted extraction and high‐performance liquid chromatography followed by chemometric analysis

Lam, Shing‐Chung, Liu, Xin, Chen, Xian‐Qiang, Hu, De‐Jun, Zhao, Jing, Long, Ze‐Rong, Fan, Bing, Li, Shao‐Ping
Journal of separation science 2016 v.39 no.15 pp. 2919-2927
Chrysanthemum morifolium, Coreopsis tinctoria, active ingredients, antioxidant activity, buds, chemometrics, chlorogenic acid, flowers, glycemic effect, high performance liquid chromatography, leaves, medicinal properties, microwave treatment, quality control, seeds, stems, tea, China
Coreopsis tinctoria, also called “snow chrysanthemum” in China, is a flower tea material that has been reported to possess excellent pharmacological properties such as antioxidant and antidiabetic activities. The chemical characteristics of different parts (flowers, buds, seeds, stems, and leaves) of C. tinctoria were investigated based on microwave‐assisted extraction and the simultaneous determination of 13 major active compounds by high‐performance liquid chromatography, including taxifolin‐7‐O‐glucoside, chlorogenic acid, (R/S)‐flavanomarein, isocoreopsin, quercetagetin‐7‐O‐glucoside, isookanin, 5,7,3′,5′‐tetrahydroxyflavanone‐7‐O‐glucoside, marein, 3,5‐dicaffeoylquinic acid, coreopsin, okanin, 5,7,3′,5′‐tetrahydroxyflavanone, and N¹,N⁵,N¹⁰,N¹⁴‐tetra‐p‐coumaroylspermine. Chemometric analysis based on the contents of investigated compounds from 13 samples showed that C. tinctoria and the related flower tea materials, Chrysanthemum morifolium cv “Hangju” and “Gongju,” were in different clusters, and different parts (flowers, buds, seeds, stems, and leaves) of C. tinctoria were obviously different. This study is helpful for the quality control and pharmacological evaluation of different parts from C. tinctoria and its related products.