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Regioselective Synthesis of Multisubstituted Furans via Copper-Mediated Coupling between Ketones and β-Nitrostyrenes
- Ghosh, Monoranjan, Mishra, Subhajit, Hajra, Alakananda
- Journal of organic chemistry 2015 v.80 no.10 pp. 5364-5368
- chemical reactions, chemical structure, furans, ketones, organic chemistry, regioselectivity
- A copper-mediated intermolecular annulation of alkyl ketones and β-nitrostyrenes has been developed for the regioselective synthesis of multisubstituted furan derivatives in good yields. This protocol is applicable to both cyclic and acyclic ketones.