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Palladium-Catalyzed Oxidative Carbonylation of Aromatic C–H Bonds of N-Alkylanilines with CO and Alcohols for the Synthesis of o-Aminobenzoates

Author:
Chen, Ming, Ren, Zhi-Hui, Wang, Yao-Yu, Guan, Zheng-Hui
Source:
Journal of organic chemistry 2015 v.80 no.2 pp. 1258-1263
ISSN:
1520-6904
Subject:
alcohols, catalytic activity, chemical bonding, chemical reactions, chemical structure, organic chemistry, palladium
Abstract:
A Pd(II)-catalyzed C–H monocarbonylation of N-alkylanilines for the synthesis of o-aminobenzoates has been developed. Various aliphatic alcohols and phenol were tolerated in the reaction to afford the corresponding o-aminobenzoates in good yields under mild balloon pressure of CO.
Agid:
5504693