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Copper-Mediated Aerobic Oxidative Synthesis of 3-Bromo-imidazo[1,2-a]pyridines with Pyridines and Enamides

Author:
Zhou, Xiaoqiang, Yan, Hao, Ma, Chaowei, He, Yongqin, Li, Yamin, Cao, Jinhui, Yan, Rulong, Huang, Guosheng
Source:
Journal of organic chemistry 2016 v.81 no.1 pp. 25-31
ISSN:
1520-6904
Subject:
chemical reactions, moieties, organic chemistry, pyridines
Abstract:
A conversion of pyridines and enamides for the synthesis of 3-bromo-imidazo[1,2-a]pyridines was developed by copper-mediated aerobic oxidative coupling in a one-pot manner. This procedure tolerates various functional groups and affords a series of 3-bromo-imidazo[1,2-a]pyridines under mild conditions.
Agid:
5505434