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Aggressive cutaneous zygomycosis caused by Apophysomyces variabilis in an immunocompetent child
- Al-Zaydani, Ibrahim A., Al-Hakami, Ahmed M., Joseph, Martin R.P., Kassem, Walid M., Almaghrabi, Mohamed K., Nageeb, Abdalla, Hamid, Mohamed E.
- Medical mycology case reports 2015 v.10 pp. 11-13
- amputation, biopsy, case studies, children, fungi, genes, males, mycology, pathogen identification, patients, ribosomal RNA, skin lesions
- A zygomycetous fungus was observed in a biopsy of a 9-year-old male. The patient was presented with severe cutaneous lesions subsequent to a traumatic car accident. Following fungal detection, antifungal treatment was prescribed but condition deteriorated rapidly and above knee amputation was done as lifesaving and to control fungal infection. Analysis of the 28S rRNA gene (accession KT149770) aligned the isolate with members of the genus Apophysomyces and the pathogen was identified as Apophysomces variabilis.