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CuI-catalyzed intramolecular cyclization of 3-(2-aminophenyl)-2-bromoacrylate: synthesis of 2-carboxyindoles

Author:
Xiao, Xiong, Chen, Tian-Qi, Ren, Jiangmeng, Chen, Wei-Dong, Zeng, Bu-Bing
Source:
Tetrahedron letters 2014 v.55 pp. 2056-2060
ISSN:
0040-4039
Subject:
chemical reactions, chemical structure, organic compounds
Abstract:
A new approach was described for the synthesis of substituted 2-carboxyindole using 3-(2-aminophenyl)-2-bromo-acrylates through a CuI-catalyzed intramolecular coupling. The reactions were mild, rapid and with good to excellent yields.
Agid:
5515734