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Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes

Author:
Ng, Cherie T., Mendoza, Juan L., Garcia, K. Christopher, Oldstone, Michael B.A.
Source:
Cell 2016 v.164 pp. 349-352
ISSN:
0092-8674
Subject:
infection, interferons, signal transduction
Abstract:
Type I interferon (IFN-I) elicits a complex cascade of events in response to microbial infection. Here, we review recent developments illuminating the large number of IFN-I species and describing their unique biologic functions.
Agid:
5517554