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Disease Tolerance Trick or Treat: Give Your Brain Something Good to Eat

Author:
Ayres, Janelle S.
Source:
Cell 2016 v.166 no.6 pp. 1368-1370
ISSN:
0092-8674
Subject:
anorexia, brain, disease resistance, motivation
Abstract:
The reprioritization of feeding motivations during disease is proposed to optimize host defense strategies against infection. Now, Wang et al. identify that sickness-induced anorexia differentially shapes the metabolic requirements of cellular stress adaptations, leading to opposite impact on disease tolerance upon bacterial versus viral infections.
Agid:
5517942