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Disease Tolerance Trick or Treat: Give Your Brain Something Good to Eat
- Ayres, Janelle S.
- Cell 2016 v.166 no.6 pp. 1368-1370
- anorexia, brain, disease resistance, motivation
- The reprioritization of feeding motivations during disease is proposed to optimize host defense strategies against infection. Now, Wang et al. identify that sickness-induced anorexia differentially shapes the metabolic requirements of cellular stress adaptations, leading to opposite impact on disease tolerance upon bacterial versus viral infections.