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Complete genome sequence of the actinobacterium Streptomyces glaucescens GLA.O (DSM 40922) consisting of a linear chromosome and one linear plasmid
- Ortseifen, Vera, Winkler, Anika, Albersmeier, Andreas, Wendler, Sergej, Pühler, Alfred, Kalinowski, Jörn, Rückert, Christian
- Journal of biotechnology 2015 v.194 pp. 81-83
- Streptomyces glaucescens, acarbose, alpha-glucosidase, chromosomes, genome, noninsulin-dependent diabetes mellitus, nucleotide sequences, plasmids
- Here we report the complete and finished genome sequence of Streptomyces glaucescens GLA.O (DSM 40922), a natural producer of the alpha-glucosidase inhibitor acarbose, which is used in the treatment of type-2 diabetes mellitus. The genome of S. glaucescens GLA.O consists of two replicons, the chromosome with a size of 7,453,200bp and a G+C content of 73.0% as well as a plasmid named pSglau1 with a size of 170,574bp and a G+C content of 69.06%.