U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

Nano-hydroxyapatite/polyacrylamide composite hydrogels with high mechanical strengths and cell adhesion properties

Author:
Zhiyong Li, Wenying Mi, Huiliang Wang, Yunlan Su, Changcheng He
Source:
Colloids and Surfaces B: Biointerfaces 2014 v.123 pp. 959-964
ISSN:
0927-7765
Subject:
cell adhesion, crosslinking, gels, hydrocolloids, micelles, mixing, nanocomposites, polyacrylamide, tensile strength, tissue engineering
Abstract:
Nano-hydroxyapatite/polyacrylamide composite hydrogels were successfully fabricated by physically mixing nano-hydroxyapatite (nHAp) particles into a peroxidized micelles initiated and cross-linked (pMIC) polyacrylamide (PAAm) hydrogel. The nanocomposite hydrogels exhibited excellent mechanical properties. The fracture tensile stresses of the gels were in the range of 0.21–0.86MPa and the fracture tensile strains were up to 30mm/mm, and the compressive strengths were up to 35.8MPa. Meanwhile the introduction of nHAp endowed the composite hydrogels with good cell adhesion properties. This nHAp/PAAm nanocomposite hydrogel is expected to find potential applications in tissue engineering.
Agid:
5530636