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Assessing the Effects of Amoxicillin on Antioxidant Enzyme Activities, Lipid Peroxidation and Protein Carbonyl Content in the Clam Ruditapes philippinarum and the Mussel Mytilus galloprovincialis

Author:
Matozzo, Valerio, Battistara, Margherita, Marisa, Ilaria, Bertin, Valeria, Orsetti, Alessandro
Source:
Bulletin of environmental contamination and toxicology 2016 v.97 no.4 pp. 521-527
ISSN:
0007-4861
Subject:
Mytilus galloprovincialis, Ruditapes philippinarum, amoxicillin, biomarkers, catalase, clams, enzyme activity, gills, lipid peroxidation, mussels, oxidative stress, superoxide dismutase
Abstract:
In this study, we evaluated the capability of amoxicillin (AMX)—one of the most widely used antibiotics worldwide—to induce oxidative stress in both gills and digestive gland from two bivalve species, the clam Ruditapes philippinarum and the mussel Mytilus galloprovincialis. Superoxide dismutase (SOD) and catalase (CAT) activities, as well as the lipid peroxidation levels (LPO) and protein carbonyl content (PCC), were measured in bivalves exposed to 100, 200 and 400 µg AMX/L for 1, 3 and 7 days. The results obtained demonstrated that AMX affected slightly biomarker responses of molluscs.
Agid:
5555522