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Branch-Selective Hydroarylation: Iodoarene–Olefin Cross-Coupling

Author:
Green, Samantha A., Matos, Jeishla L. M., Yagi, Akiko, Shenvi, Ryan A.
Source:
Journal of the American Chemical Society 2016 v.138 no.39 pp. 12779-12782
ISSN:
1520-5126
Subject:
chemical reactions, cobalt, hydrogen, nickel, olefin
Abstract:
A combination of cobalt and nickel catalytic cycles enables a highly branch-selective (Markovnikov) olefin hydroarylation. Radical cyclization and ring scission experiments are consistent with hydrogen atom transfer (HAT) generation of a carbon-centered radical that leads to engagement of a nickel cycle.
Agid:
5560561