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Clerodens E–J, antibacterial caffeic acid derivatives from the aerial part of Clerodendranthus spicatus

Author:
Li, Qing, He, Ying-Na, Shi, Xiao-Wei, Kang, Li-Ying, Niu, Li-Ying, Wang, Xin-Guo, Feng, Wei
Source:
Fitoterapia 2016 v.114 pp. 110-114
ISSN:
0367-326X
Subject:
Orthosiphon aristatus, aerial parts, antibacterial properties, bacteria, caffeic acid, drug resistance, medicinal plants, nuclear magnetic resonance spectroscopy
Abstract:
Six new caffeic acid derivatives, Clerodens E–J (1–6) were isolated from the aerial part of Clerodendranthus spicatus. Their structures were elucidated by extensive spectroscopic analysis, including NMR, MS, and ECD data. Compound 1 showed moderate antibacterial activities against drug-resistant strains of bacteria in vitro.
Agid:
5570837