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Cooperative action in DNA condensation
- Jorge, Andreia F., Nunes, Sandra C.C., Cova, Tânia F.G.G., Pais, Alberto A.C.C.
- Current opinion in colloid & interface science 2016 v.26 pp. 66-74
- DNA, electrostatic interactions, synergism
- In this review we address the two main sets of strategies for DNA compaction and condensation, those based on electrostatic interactions and those based on space restrictions, including confinement and excluded volume. Focus will be given to work in which these overall strategies are combined in multi-factorial approaches, thus promoting cooperative and synergistic effects. Discussion includes bio-motivated and bio-inspired work. Recent work is reviewed, and an effort is made to extract general trends and characterize the overall behaviour.