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Two new sesquiterpenoids produced by halophilic Nocardiopsis chromatogenes YIM 90109

Author:
Sun, Ming-Wei, Zhang, Xiao-Mei, Bi, Hui-Li, Li, Wen-Jun, Lu, Chun-Hua
Source:
Natural product research 2017 v.31 no.1 pp. 77-83
ISSN:
1478-6427
Subject:
Nocardiopsis, X-ray diffraction, antibacterial properties, nuclear magnetic resonance spectroscopy, sesquiterpenoids, spectral analysis
Abstract:
Two new germacradiene-type sesquiterpenoids, including 1(10) E ,5 E -germacradiene-9 β ,11-diol (or 9 β -hydroxyl germacradienol) (1) and 11-hydroxy-1(10) E ,5 E -germacradien-2-one (2-oxygermacradienol) (2), together with a known geosmin-type sesquiterpenoid (1 β ,4 β ,4a β ,7 α ,8a α)-4,8a-dimethyloctahydronaphthalene-1,4a,7(2H)-triol (3), were elucidated by their NMR spectroscopic data, HR–ESI–MS and single-crystal X-ray diffraction from the halophilic strain Nocardiopsis chromatogenes YIM 90109. The antimicrobial activities were evaluated by paper diffusion method.
Agid:
5588670