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A new flavonol glycoside from the aerial parts of Epimedium koreanum Nakai

Author:
Han, Fubo, Lee, Ik-Soo
Source:
Natural product research 2017 v.31 no.3 pp. 320-325
ISSN:
1478-6427
Subject:
2,2-diphenyl-1-picrylhydrazyl, Epimedium koreanum, aerial parts, antioxidant activity, chemical structure, flavonols, free radical scavengers, glycosides, methanol, spectroscopy
Abstract:
A new prenylated flavonol glycoside (1) was isolated from a 95% methanol extract of the dried and powdered aerial parts of Epimedium koreanum Nakai (Herba Epimedii), along with seven previously known flavonoids (2 – 8). The chemical structure of the new compound (1) was established to be 5-hydroxy-4′-methoxy-8-(2-hydroxy-3-methyl-3-butenyl)flavone 3- O -α- l -rhamnopyranosyl-7- O -β-D-gluco pyranoside on the basis of spectroscopic methods. The antioxidant activities of these compounds were determined by the DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical scavenging assay and kaempferitrin (8) showed a high reactivity with DPPH.
Agid:
5588710