Jump to Main Content
Synthesis of phenanthridinones using Cu- or Pd-mediated CN bond formation
- Nealmongkol, Prattya, Calmes, Jordan, Ruchirawat, Somsak, Thasana, Nopporn
- Tetrahedron 2017 v.73 pp. 735-741
- amines, catalysts, chemical reactions, chemical structure, copper, ligands, palladium, solvents
- The chemoselective synthesis of phenanthridinones was studied using copper(I)- and palladium(II)-catalyzed CN bond formation with various bases, ligands, and solvents. Phenanthridinones were obtained from 2-halobiarylcarboxylates and amines in a one-pot reaction. The phenanthridinones and heterocyclic-fused lactam derivatives were accomplished using developed methods.