PubAg

Main content area

Palladium-catalysed α-Allylation of Chiral Sulfinimines Derived from Symmetric Cyclic Ketones

Author:
Li, Jiangnan, Dawood, Rafid S., Qin, Shuanglin, Liu, Tongtong, Liu, Shuangwei, Stockman, Robert A., Jiang, Shende, Yang, Guang
Source:
Tetrahedron letters 2017
ISSN:
0040-4039
Subject:
catalytic activity, chemical reactions, chemical structure, ketones, ligands, palladium, phosphine
Abstract:
A diastereoselective mono-allylation reaction at the α-position of symmetric cyclic ketones by using tert-butanesulfinamide as a chiral auxiliary is explored. Excellent yields and high diastereomeric ratios were achieved under palladium(0) catalysis in the presence of a readily available achiral phosphine ligand.
Agid:
5631990