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Açai (Euterpe oleracea Mart.) dietary intake affects plasma lipids, apolipoproteins, cholesteryl ester transfer to high-density lipoprotein and redox metabolism: A prospective study in women

Author:
Pala, Daniela, Barbosa, Priscila Oliveira, Silva, Carla Teixeira, de Souza, Melina Oliveira, Freitas, Fatima Rodrigues, Volp, Ana Carolina Pinheiro, Maranhão, Raul Cavalcante, Freitas, Renata Nascimento de
Source:
Clinical nutrition 2017
ISSN:
0261-5614
Subject:
Euterpe oleracea, antioxidant activity, antioxidants, apolipoproteins, aryldialkylphosphatase, atherosclerosis, biomarkers, blood lipids, blood sampling, cholesteryl esters, food intake, functional foods, glucose, high density lipoprotein cholesterol, insulin, low density lipoprotein, malondialdehyde, metabolism, phospholipids, polyphenols, prospective studies, pulp, triacylglycerols, women, Amazonia, Brazil
Abstract:
The açai fruit (Euterpe oleracea Martius), which is native to the Brazilian Amazon region, was shown to have high polyphenols and MUFA contents. In this study, we aimed to assess the effects of açai consumption on plasma lipids, apolipoproteins, the transfer of lipids to HDL (which is a relevant HDL function), and some biomarkers of redox metabolism. Forty healthy volunteer women aged 24 ± 3 years consumed 200 g of açai pulp/day for 4 weeks; their clinical variables and blood sample were obtained before and after this period. Açai pulp consumption did not alter anthropometric parameters, systemic arterial pressure, glucose, insulin and total, LDL and HDL cholesterol, triglycerides and apolipoprotein (apo) B, but it did increase the concentration of apo A-I. Açai consumption decreased the ROS, ox-LDL and malondialdehyde while increasing the activity of antioxidative paraoxonase 1. Overall, the total antioxidant capacity (TAC) was increased. Regarding the transfer of plasma lipids to HDL, açai consumption increased the transfer of cholesteryl esters (p = 0.0043) to HDL. Unesterified cholesterol, phospholipids and triglyceride transfers were unaffected. The increase in apo A-I and the cholesteryl ester transfer to HDL after the açai intake period suggests that an improvement in the metabolism of this lipoprotein occurred, and it is well known that HDL is protective against atherosclerosis. Another important finding was the general improvement of the anti-oxidant defences elicited by açai consumption. Our data indicate that açai has favourable actions on plasma HDL metabolism and anti-oxidant defence; therefore açai could have a beneficial overall role against atherosclerosis, and it is a consistently good candidate to consider as a functional food.
Agid:
5638817