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Nortriterpenoids from the stems and leaves of Schisandra viridis

Author:
Liu, Ye, Tian, Tian, Yu, Heng-Yi, Zhou, Ming, Ruan, Han-Li
Source:
Fitoterapia 2017 v.118 pp. 38-41
ISSN:
0367-326X
Subject:
Schisandra, antineoplastic activity, chemical structure, cytotoxicity, leaves, neoplasms, nuclear magnetic resonance spectroscopy, stems
Abstract:
An extensive phytochemical study on the stems and leaves of Schisandra viridis A. C. Smith led to the isolation of two novel highly oxygenated schinortriterpenoids, pre-schisanartanin P (1) and wuweizidilactone Q (2), together with four known ones (3–6). Their structures with absolute configurations were established on the basis of comprehensive spectroscopic methods, including HRESIMS, 1D and 2D NMR analyses and ECD experiments. All isolates were evaluated for their in vitro cytotoxicities against HepG2, MCF-7 and HT-29 cancer cell lines, none of them showed significant activities.
Agid:
5641751