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Liamocin oil from Aureobasidium pullulans has antibacterial activity with specificity for species of Streptococcus

Author:
Bischoff, Kenneth M., Leathers, Timothy D., Price, Neil P J, Manitchotpisit, Pennapa
Source:
The Journal of Antibiotics 2015 v.68 no.10 pp. 642-645
ISSN:
0021-8820
Subject:
Aureobasidium pullulans, Enterococcus faecalis, Escherichia coli, Lactobacillus fermentum, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus agalactiae, Streptococcus mutans, antibacterial properties, antibiotics, minimum inhibitory concentration, oils, pathogens
Abstract:
Liamocin oil from Aureobasidium pullulans NRRL 50380 was tested for antibacterial activity. Liamocins inhibited growth of Streptococcus agalactiae, S. uberis, S. mitis, S. infantarius, and S. mutans, with minimum inhibitory concentrations from 20 'g/ml to 78 'g/ml. Enterococcus faecalis was less susceptible (MIC = 312 'g/ml), while Staphylococcus aureus, Lactobacillus fermentum, Escherichia coli, and Pseudomonas aeruginosa had MICs > 1,250 'g/ml. Liamocins may be developed as a narrow spectrum antimicrobial agent that targets streptococcal pathogens.
Agid:
5642485
Handle:
10113/5642485