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Memory Is the Treasury and Guardian of All Things
- D’Urso, Agustina, Brickner, Jason H.
- Molecular cell 2017 v.66 no.1 pp. 5-6
- ecdysone, enhancer elements, nuclear membrane, porins, promoter regions, transcription (genetics)
- Transcriptional memory often relies on interactions with nuclear pore proteins. In this issue of Molecular Cell, Pascual-Garcia et al. (2017) describe hormone-induced developmental transcriptional memory in cells that have previously experienced ecdysone, mediated by Nup98-dependent enhancer-promoter looping.