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Transition-metal-free synthesis of quinolines from 2-nitrobenzyl alcohol in water
- Zhu, Meijuan, Wang, Chao, Tang, Weijun, Xiao, Jianliang
- Tetrahedron letters 2015 v.56 pp. 6758-6761
- alcohols, catalysts, chemical reactions, chemical structure, quinolines
- A method for the synthesis of quinolines from cheap and readily available 2-nitrobenzyl alcohol without a transition-metal catalyst in water has been developed, providing a convenient method for accessing quinolines. The reaction features an intramolecular redox process, which generates the key intermediate leading to product formation.