U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation

Author:
Huawei Zeng, Jay J. Cao, Gerald F. Combs
Source:
Nutrients 2013 v.5 no.1 pp. 97-110
ISSN:
2072-6643
Subject:
antioxidants, bone metabolism, bones, cell proliferation, dietary minerals, humans, immune response, selenium
Abstract:
Selenium (Se) is an essential trace element for humans and animals, and several findings suggest that dietary Se intake may be necessary for bone health. Such findings may relate to roles of Se in antioxidant protection, enhanced immune surveillance and modulation of cell proliferation. Elucidation of the mechanisms by which Se supports these cellular processes can lead to a better understanding of the role of this nutrient in normal bone metabolism. This article reviews the current knowledge concerning the molecular functions of Se relevant to bone health.
Agid:
56738
Handle:
10113/56738