Jump to Main Content
Live-Cell Nanoscopy in Antiadhesion Therapy
- Geoghegan, Joan A., Foster, Timothy J., Speziale, Pietro, Dufrêne, Yves F.
- Trends in microbiology 2017 v.25 no.7 pp. 512-514
- Staphylococcus aureus, adhesion, glycoconjugates, monoclonal antibodies, pathogens, synthetic peptides, technology, therapeutics, uropathogenic Escherichia coli
- Live-cell nanoscopy has contributed significantly to assessing the inhibition of adhesion of uropathogenic Escherichia coli and Staphylococcus aureus by glycoconjugates and monoclonal antibodies, respectively, and of S. aureus surface attachment and cell–cell association by a synthetic peptide. This new technology shows promise for the development of antiadhesion therapies against bacterial pathogens.