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Changes of serum myeloperoxidase and nitric oxide in the early stage of Edwardsiella ictaluri infection in channel catfish, Ictalurus punctatus (Rafinesque)

Author:
Yeh, H. Y., Klesius, P. H.
Source:
Journal of fish diseases 2013 v.36 no.4 pp. 441
ISSN:
1365-2761
Subject:
Edwardsiella ictaluri, Ictalurus punctatus, biomarkers, blood serum, catfish, disease control, expressed sequence tags, farmed fish, fish diseases, hatcheries, health status, infectious diseases, monitoring, mortality, myeloperoxidase, nitric oxide, ponds, septicemia
Abstract:
Enteric septicemia of catfish (ESC), caused by Edwardsiella ictaluri, is an important farm-raised channel catfish, Ictalurus punctatus (Rafinesque), disease. The development of a monitoring system for assessing the catfish health status in hatcheries and ponds is in great demanding. Because of the easy access of blood, which collects and transport many normal and abnormal materials, serum is an attractive place to begin with for searching potential biomarkers for infectious diseases. Previously, we observed the up-regulation of some expressed sequence tags (EST) after channel catfish infected with Edwardsiella ictaluri. In this communication, we examined two serum components-myeloperoxidase and nitric oxide-in the early stage of ESC in channel catfish. Our data demonstrate that serum myeloperoxidase increased within 24 hr after infection, while nitric oxide (NO) reached the peak at day 7 post infection. In addition, the mortality occurred between day 4 and day 5 post infection. Whether the mortality correlates with the changes of myeloperoxidase and NO in catfish sera is under investigation. The findings were interesting and indicated that incorporation of monitoring serum myeloperoxidase and NO in the aquacultural management may benefit the producers in controlling infectious disease.
Agid:
56893
Handle:
10113/56893